According to Daft Punk, once again. On Oct. 25, the U.S. Food and Drug Administration (FDA) announced another recall of high blood pressure drugs for contaminants that can cause cancer, a problem that has arisen too many times since 2017. This time the company is Aurobindo Pharma USA, Inc. The hypertension medication to be recalled is USP’s quinapril and hydrochlorothiazide tablets in doses of 20 mg and 12.5 mg, respectively. And the contaminant is an impurity associated with the drug substance nitrosamine( NNRSN), N-Nitrosoquinapril, in amounts exceeding the allowable limits.
This is definitely not a “we will celebrate” situation. Although nitrosamines may be present in water and foods such as salted and grilled meats, dairy products and vegetables, repeated ingestion of nitrosamines over long periods of time can increase the risk of cancer. That’s why the FDA has set thresholds for acceptable levels of nitrosamines in drugs. Although there have been no reports yet of side effects associated with taking drugs recalled by Aurobindo Pharma USA, Inc. at this point, the presence of too high levels of nitrosamines means that the company will have to fix things and do a little cleanup of its manufacturing processes.
So check your blood pressure medications. The recall does not cover all high blood pressure medications under the sun or the moon, for that matter. It only includes certain batches of Quinapril and Hydrochlorothiazide USP 20 mg / 12.5 mg tablets supplied by Aurobindo Pharma USA, Inc. And these shipments are numbered QE2021005-A or QE2021010-A and were shipped as of May 2021. You can check the drug label for the National Drug Code (NDC) number 65862-162-90 and the expiration date 01/2023 on the label. The tablets are pink, round, biconvex, and film-coated with a “D” on one side and a “19” on the other. If you are still not able to determine if your drugs are covered under the recall, call the pharmacist who gave you the drugs.
If your medications fall under the recall, don’t stop them right away. Blood pressure medications are not like hot dogs. You may not be able to stop them with a cold turkey or, rather, a cold hot dog. Abruptly stopping your high blood pressure medication can lead to dangerous blood pressure spikes. Therefore, ask your doctor for advice on what to do first as soon as possible. Once you and your doctor decide what to do, you can return the medication for reimbursement. In fact, you may get a call from Qualanex on behalf of Aurobindo Pharma USA, Inc. if they become aware that you are taking medications covered by the recall. So if they call you, don’t just say, “Hey, I don’t need what you’re selling,” or “I thought I left that dating app a long time ago. “Instead, listen to what they have to say.
If this all sounds like déjà vu again, it is. It’s actually deja vu from deja vu from deja vu. I’ve already covered for Forbes similar high blood pressure drug recalls from Pfizer in March 2022, from Lupin Pharmaceuticals Inc. in October 2021, from Torrent Pharmaceuticals Limited in September 2019, from Hetero Labs Ltd.in May 2019 and from a host of other companies. in 2018. As the saying goes, once can be an accident. Perhaps it’s a coincidence. Three times not a lady, but a model. And four, and five, and six, and many more times means you have to do more.
This latest review of high blood pressure medications reminds us once again that there is still much work to be done to determine how safe our medication supply is. As pharmaceutical manufacturers expand their supply chains around the world and try to find cheaper ways to produce drugs, you have to wonder to what extent regulations are followed and processes are controlled. The consequences of drug manufacturing violations are far more serious than sweatshirt manufacturing violations. Even if your sweatshirt had extra hoods or was the wrong color, such as bright yellow urine, the problems would be easily seen and reversible. So if this person didn’t want to date you just because your sweatshirt had four hoods and you looked like a giant daffodil. On the other hand, medication defects may
